基本信息
马海昊,华中师范大学动物学博士,现任湖南省农业科学院植物保护研究所副研究员,湖南大学隆平农学院兼职硕导。从事杀虫剂毒理学研究和杀虫剂新靶标挖掘工作,以第一作者或通讯作者(含共同)在Pest Management Science、Pesticide Biochemistry and Physiology、Insects、International Journal of Molecular Sciences 、Archives of Insect Biochemistry and Physiology、Scientific Reports 等昆虫学主流期刊上发表SCI论文10余篇。主持国家自然科学基金青年项目1项、国家重点研发计划课题1项、子课题1项、湖南省自然科学基金2项。
教育背景
2011.09– 2016.06,华中师范大学,动物学专业,博士生
2008.09– 2011.06,河南大学,微生物学专业,硕士生
2004.09– 2008.06,河南大学,生物技术专业,学士术学院,本科生
工作履历
2025.01~至今 湖南省农业科学院植物保护研究所,副研究员
2021.12~2024.12 湖南省农业科学院农业生物技术研究所,副研究员
2021.06~至今 湖南大学研究生院隆平分院,硕导
2017.03~2021.11 湖南省农业科学院农业生物技术研究所,助理研究员
学术兼职
第十四届中国植物保护学会园艺病虫害专委会,委员
研究领域
杀虫剂的使用推动了现代农业的发展。目前约有80%的商品化杀虫剂通过作用于细胞离子通道,扰乱昆虫神经系统来控制害虫危害。探索杀虫剂作用的离子通道、发现害虫体内可以作为杀虫剂靶标的新型离子通道有助于我们深入了解现有杀虫剂的作用机制和开发具有自主知识产权的新型绿色高效杀虫剂。本团队专注于害虫体内重要离子通道的结构、功能和药理学性质研究,并致力于害虫的绿色防控技术研发与技术集成,服务于农业绿色可持续发展的国家重大战略。
科研项目
1. 国家重点研发计划子课题(2023YFF1401205-3),主持,在研(2023-2027)
2. 湖南省自然科学基金面上项目(2023JJ30343),主持,在研(2023-2025)
3. 国家重点研发计划课题(2019YFD1002104),主持,结题(2019-2022)
4. 国家自然科学基金青年基金(31701811),主持,结题 (2018-2020)
5. 湖南省自然科学基金青年项目(2018JJ3290),主持,结题(2018-2020)
学术成果
1.Xiaoyi Huo, Xiaomao Zhou*, Zheming Liu, Piao Zhao, Jia Liu, Hang Zhu, Yong Zhou, Yilong Man, Chengjia Zhang, Haihao Ma*. Genetic and pharmacological inhibition of Kir1 impacts mating behavior of the diamondback moth (Plutella xylostella). Pest Management Science (2025). doi: 10.1002/ps.70160.
2.Yinna Wang, Haihao Ma*, Zheming Liu, Piao Zhao, Jia Liu, Hang Zhu, Yong Zhou, Yilong Man, Xiaomao Zhou*. The Elongation Factor 1 Alpha Promoter Drives the Functional Expression of Kir2A in Plutella xylostella Cells. International Journal of Molecular Sciences (2025) 26(7):3042. doi: 10.3390/ijms26073042.
3.Xiaoyi Huo#, Yinna Wang#, Zheming Liu, Jia Liu, Hang Zhu, Yong Zhou, Yilong Man, Xiaomao Zhou, Haihao Ma*. Electrophysiological and pharmacological properties of the slowpoke channel in the diamondback moth, Plutella xylostella. Pesticide Biochemistry and Physiology (2024) 200:105824. doi: 10.1016/j.pestbp.2024.105824.
4.Wei Zheng, Haihao Ma, Zhangyang Liu, Yong Zhou, Hang Zhu, Jia Liu, Chengjia Zhang, Zheming Liu*, Xiaomao Zhou*. Knockout of tyramine receptor 1 results in a decrease of oviposition, mating, and sex pheromone biosynthesis in female Plutella xylostella. Pest Management Science (2023) 79(10):3903-3912. doi: 10.1002/ps.7571.
5.Haihao Ma, Xiumei Yan, Lin Yan, Jingyan Zhao, Jiping Song, Rong Peng, Yongbo Yang, Jianxin Peng, Kaiyu Liu*. Identification and Functional Analysis of Apoptotic Protease Activating Factor-1 (Apaf-1) from Spodoptera litura. Insects (2021) 12(1):64. doi: 10.3390/insects12010064.
6.Jie Xu, Haihao Ma*, Zheming Liu, Wei Zheng, Xiaoyi Lai, Hang Zhu, Jia Liu, Yong Zhou and Xiaomao Zhou*, Expression and Alternative Splicing Analysis of a Large-conductance Calcium-activated Potassium Channel Gene in Plutella xylostella, Archives of Insect Biochemistry and Physiology (2020) 17:e21720. doi: 10.1002/arch.21720.
7.Xiaoyi Lai, Jie Xu, Haihao Ma*, Zheming Liu, Wei Zheng, Jia Liu, Hang Zhu, Yong Zhou and Xiaomao Zhou*. Identification and Expression of Inward-Rectifying Potassium Channel Subunits in Plutella xylostella. Insects (2020) 11(8):E461. doi: 10.3390/insects11080461.
8.Jie Xu, Zanyong Wang, Yafei Wang, Haihao Ma*, Hang Zhu, JiaLiu, Yong Zhou, Xile Deng and Xiaomao Zhou*. ABCC2 participates in the resistance of Plutella xylostella to chemical insecticides. Pesticide Biochemistry and Physiology (2019) 162:52-59. doi: 10.1016/j.pestbp.2019.08.010.
9.Haihao Ma, Qingting Huang, Xiaoyi Lai, Jia Liu, Hang Zhu, Yong Zhou, Xile Deng and Xiaomao Zhou*. Pharmacological Properties of the Type 1 Tyramine Receptor in the Diamondback Moth, Plutella xylostella. International Journal of Molecular Sciences (2019) 20, 2953. doi: 10.3390/ijms20122953.
10Qingting Huang, Haihao Ma*, Xile Deng, Hang Zhu, Jia Liu, Yong Zhou and Xiaomao Zhou*. Pharmacological Characterization of a Beta-adrenergic-like Octopamine Receptor in Plutella xylostella. Archives of Insect Biochemistry and Physiology (2018) 98(4): e21466. doi: 10.1002/arch.21466.
11Haihao Ma, Yuemin Ma, Xuehui Liu, David H Dyer, Pingyong Xu, Kaiyu Liu, Que Lan, Huazhu Hong, Jianxin Peng* and Rong Peng*. NMR structure and function of Helicoverpa armigera sterol carrier protein-2, an important insecticidal target from the cotton bollworm. Scientific Reports (2015) 5:18186. doi: 10.1038/srep18186.
奖励与荣誉
1. 湖南省农业科学院青年英才奖,2021
2. 湖南省自然科学奖三等奖,2021
3. 湖南省农业科学院自然科学奖一等奖,2020
招生信息
每年计划招收硕士生1-2名(含免试推荐、申请-考核制、统考等来源)。
常年接收联合培养研究生、本科生等进行科研训练。热烈欢迎有志于农药学或农业昆虫学研究者随时联系、加入本团队!
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