，1988年生，河北石家庄人，现任湖南省农产品加工与质量安全研究所副研究员、湖南大学隆平农学院硕导。长期从事食品营养与肠道/肝脏健康研究，以第一作者或共同第一作者在Journal of Genetics and Genomics、Journal of Advanced Research、Cell Death and Differentiation、Research、Critical Reviews in Food Science and Nutrition、Journal of Agricultural and Food Chemistry等顶尖期刊发表研究论文，多项成果入选中ESI高被引论文。

团队研究方向

主要研究方向包括：食品营养与MASLD防控；内源性代谢物与肠道肝脏健康；超加工食品、食品质量安全与健康；代谢途径优化设计与加工副产物综合利用。

教育背景

2017.9-2019.9  德州农工大学营养学院，营养学， 联合培养博士研究生（导师：Shaodong Guo教授）

2014.0−2017.9 华中农业大学大学食品科技学院，食品科学专业，博士研究生（导师：孙智达教授）

2012.9−2014.6 华中农业大学大学食品科技学院，食品工程专业，硕士研究生（导师：孙智达教授）

2008.9−2012.6 华中农业大学大学食品科技学院，食品质量与安全专业，本科生（导师：邵艳春/刘睿教授）

工作履历

2025.12−至今 湖南省农产品加工与质量安全研究所，副研究员

2025.05−至今 湖南大学隆平农学院，副研究员/硕导

2026.09−2027.2  上海交通大学农业与生物学院，访问学者

2022.10−2025.11  湖南省农产品加工与质量安全研究所 助理研究员

2019.10−2022.08  浙江大学医学院，博士后/助理研究员

科研项目

1. 国家自然科学基金面上项目，主持，50万元，在研（2027-2030）

2. 国家自然科学基金青年科学基金项目（C类），主持，30万元，结题（2023-2025）

3. 国家重点研发计划子课题，主持，30万元，在研（2023-2027）

4. 湖湘青年英才，主持，30万元，在研（2024-2027）

5. 湖南省自然科学基金面上项目，主持，5万元，在研（2026-2028）

6. 湖南省自然科学基金青年基金项目（C类），主持，5万元，结题（2023-2025）

7. 湖南省省级人才省校合作项目（上海交通大学），主持，在研（2026-2027）

部分学术成果

（#共同第一作者；*共同通讯作者）

1，Xiaopeng Li, Yanhan Feng, Boyao Tang, Enjun Xie, Jiaming Wang, Junxia Min*, Fudi Wang*, Zhidan Xia*. Sex-specific regulation of SLC39A11 in the murine liver. Journal of Genetics and Genomics, 2026, 1673.

2, Ruxuan chen, Xionghui wu, Ning Yin, enjun Xie, Shumin Sun, Jie Shen, Yunmei chen,Fenghua Zhoug, tao lia, Qili li, Donglin Su, Fuhua Fu, Gaoyang Li*, Xiaopeng Li*, and Yang Shan*. Mechanisms of flavonoid-mediated amelioration of MASLD: flavonoids, their metabolites or impact on gut microbes? Critical Reviews in Food Science and Nutrition, 2026, 66, 12, 2287-2310.

3, Xiaopeng Li*, Enjun Xie, Shumin Sun, Jie Shen, Yujin Ding, Jiaqi Wang, Xiaoyu Peng, Ruting Zheng, Mohamed A. Farag, Jianbo Xiao*. Flavonoids for gastrointestinal tract local and associated systemic effects: A review of clinical trials and future perspectives. Journal of Advanced Research, 2025, 77, 19-41.

4, Xiaopeng Li. An Improved Two‐Step Collagenase Perfusion Protocol for Isolation of Mouse Primary Hepatocytes. Future Postharvest and Food, 2025, 00, 1-4.

5, Zhidan Xia#, Biyao Tang#, Xiaopeng Li#, Xinran Li#, Yangfan Jia, Jianwei Jiang, Jingyao Chen, Jingshu Song, Siyi Liu, Junxia Min*, Fudi Wang*. A novel role for the longevity-associated protein SLC39A11 as a manganese transporter. Research, 2024, 0440.

6, Enjun Xie, Yunmei Chen, Wanbao Yang, Quan Pan, James Zheng Shen, Fenghua Zhou,Jie Shen, Tao Li, Qili Li, Xiaopeng Li*. Long-term exposure to dietary emulsifier Tween 80 promotes liver lipid accumulation and induces different-grade inflammation in young and aged mice. Food Research International, 2024,184,114205.

7, Junyi Chen#, Xiaopeng Li#, Chaodong Ge#, Junxia Min*, Fudi Wang*. The Multifaceted Role of Ferroptosis in Liver Disease. Cell Death and Differentiation, 2022, 29(3):467-480.

8, Xiaoqin Guo#, Xiaopeng Li#, Wanbao Yang#, Wang Liao, James Zheng Shen, Weiqi Ai,Quan Pan, Yuxiang Sun, Kebin Zhang, Rui Zhang, Yuyang Qiu, Qian Dai, Hongting Zheng, Shaodong Guo*. A New Mechanism of Metformin by Targeting Foxo1 in Control of Glucose Homeostasis. Biomolecules, 2021, 11 (6),873.

9, Xiaopeng Li, Yong Sui, Bijun Xie, Zhida Sun, Shuyi Li*. Diabetes diminishes typical metabolite of litchi pericarp oligomeric procyanidins (LPOPC) in urine mediated by imbalanced gut microbiota. Food & Function.2021,12,5375-5386.

10, Xiaopeng Li, Yunmei Chen, James Zheng Shen, Quan Pan, Wanbao Yang,Hui Yan, Huimin Liu, Weiqi Ai, Wang Liao, Shaodong Guo*. Epigallocatechin gallate (EGCG) inhibits hepatic glucose production through antagonizing glucagon signaling pathway and suppressing transcriptional factor FoxO1. Journal of Agricultural and Food Chemistry, 2019,67(13), 3651-3661.

11, Hang Xu#, Xiaopeng Li#, Karen Kubena, Shaodong Guo*. Kinase Signaling in Control of Metabolic Syndrome and Dietary Intervention. International Journal of Molecular Sciences, 2019, 20 (1),128.

12. Xiaopeng Li, Ya Chen, Shuyi Li, Mo Chen,Juan Xiao, Bijun Xie, Zhida Sun*. Oligomer procyanidins from lotus seedpod (LSOPC) improves lipid homeostasis partially by modifying fat emulsification and digestion in small intestine model system. Journal of Agricultural and Food Chemistry, 2019, 67, 16, 4524–4534.

13. Xiaopeng Li, Shuyi Li, Mo Chen, Jingyi Wang, Bijun Xie, Zhida Sun*. (-)-Epigallocatechin-3-gallate (EGCG) inhibits starch digestion and improves glucose homeostasis through direct or indirect activation of PXR/CAR-mediated phase Ⅱ metabolism in diabetic mice. Food & Function.2018,9, 4651-4663.

14. Li Xiaopeng, Qian Wu, Yong Sui, Shuyi Li, Bijun Xie, Zhida Sun*. Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice. Journal of Functional Foods. 2018,44,155-165.

15. Shuyi Li#, Li Xiaopeng#, Shpigelman, Lorenzo, Jose M., Francisco Jose*. Direct and indirect measurements of enhanced phenolic bioavailability from litchi pericarp procyanidins by Lactobacillus casei-01. Food & Function. 2017,8,2760-277.

16. Li Xiaopeng, Yong Sui, Qian Wu, Bijun Xie, Zhida Sun*. Attenuated mTOR signaling and enhanced glucose homeostasis by dietary supplementation with oligomeric procyanidins derived from lotus seedpod in streptozotocin (STZ)-induced diabetic mice. Journal of Agricultural and Food Chemistry. 2017, 65(19),3801-3810.

17. Li Xiaopeng Yong Sui, Shuyi Li, Bijun Xie, Zhida Sun*. A-type procyanidins from litchi pericarp ameliorate hyperglycemia by regulating hepatic and muscle glucose metabolism in streptozotocin (STZ)-induced diabetic mice fed with high fat diet. Journal of Functional Foods, 2016, 27,711-722.

人才招聘与研究生招生

课题组长期招聘招收博士（1名/每年）、硕士研究生（1-2名/每年）。团队欢迎食品科学、营养等专业背景的青年人才加入。

课题组将提供分子营养、细胞/动物实验等系统训练，以及与国内外优秀团队合作、深造和职业发展的机会。

欢迎有志于食品营养与肠道/肝脏相关研究的青年人才加入团队。

联系方式

联系方式：xiaopengli@hunaas.cn